After conducting a little research (i.e. ten minutes on Wikipedia), the Literary Man was able to cobble together this brief checklist of Famous Writers from Boston, which includes a few of his favorites. There are surprisingly few from Boston proper, but the list has been expanded to include those from the greater area surrounding Boston, well, okay, all of Massachusetts, really:

Louisa May Alcott (who is totally not fucking around)
Elizabeth Bishop at Vassar.
Nate Hawthorne says "Harumph!"
Tom Perrotta, whose movies are probably from pretty good books.
In summary, lots of 19th century peeps, but what’s up with Boston in the 20th and 21st centuries? Falling behind New York City, it seems like. . .